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he adrenal glands, is usually accompanied by osteoporosis. PETER L. PETRAKIS ------------------------------------------------------------------------------- <RETURN> to continue, <Q>UIT for a new search, or <R> to REPEAT this display 1 - Bone diseases 2 - Geriatrics 3 - Osteoporosis ALL ITEMS HAVE BEEN DISPLAYED. ENTER <LINE NUMBER> TO DISPLAY FULL RECORD <Q>UIT FOR NEW SEARCH 1 WORKING... ------------------------------------------------------------------------------- TITLE(s): bone diseases Bone diseases most directly influence the abilty to walk or to move any part of the body--hands, limbs, neck, and spine. They are related to joint disorders--ARTHRITIS, COLLAGEN DISEASE, DISLOCATION of joints, and RHEUMATISM. The medical specialty pertaining to bone disorders is ORTHOPEDICS. Fractures are the most common bone disorders. They can occur as the result of an accident or be secondary to metabolic diseases. Fractures are life-threatening to aged people having the metabolic bone disease OSTEOPOROSIS, in which bones become porous and brittle. A person, mostly women, having osteoporosis may break a hip during a fall and possibly die from complications. Birth Defects. Congenital bone diseases constitute a wide spectrum, ranging from the unimportant--for instance, mild bow legs--to severe lesions, such as spina bifida, in which the lower end of the spine fails to develop properly and the baby is born with paralysis and misshapen vertebrae. Congenital diseases may more follows -- press <RETURN> have hormonal bases: for example, fibrous DYSPLASIA, in which fibrous tissue replaces that of some bones, often results in bone deformity; in addition, some girls with this disease physically mature so early that they are capable of pregnancy and childbirth at the age of seven. Congenital defects also may have genetic bases, as in families who have extra fingers or toes or in the disease osteogenesis imperfecta, in which children have such brittle bones that many are fractured. Disorders of growth and development include several kinds of dwarfism and gigantism. Bones or limbs may develop deformity as the result of known causes, such as the infection poliomyelitis, or unknown or variable causes, such as curvature of the spine (SCOLIOSIS) or CLUBFOOT. Infections. Infections of bone, called osteomyelitis, are usually caused by pus-producing bacteria, especially Staphylococcus and Streptococcus. Before the development of antibiotics, children frequently contracted this disease. Today bone infections are introduced primarily through fractures and during surgical operations. People infected with syphilis, tuberculosis, leprosy, or yaws are susceptible to bone damage. Virus infections and parasitic infestations, however, rarely cause bone damage. more follows -- press <RETURN> (P for previous page) Metabolic Disorders. Metabolic abnormalities often involve defects in the storage of minerals, particularly calcium and phosphate ions, in the skeleton. Diseases of the kidney can cause a metabolic imbalance of phosphate and calcium so that weakening of the bone occurs. Other metabolic bone diseases are osteoporosis, gout, OSTEOARTHRITIS, and PAGET'S DISEASE. Nutritional Disorders. Nutritional deficiencies that result in bone damage include RICKETS in children and osteomalacia in adults, caused by a lack of vitamin D. In children, calcium and phosphate are poorly distributed on bones during development, resulting especially in deformity of the legs and arms. In adults, bones of the spine, pelvis, and legs become demineralized and the bones weaken. SCURVY--caused by a lack of vitamin C--also affects bone tissues. Toxic Diseases. more follows -- press <RETURN> (P for previous page) The importance of toxic conditions of bones to public health became evident because of such tragedies as thalidomide-induced birth defects and radium poisoning. The drug THALIDOMIDE was given to pregnant women in England and Germany for use as a sleeping pill and to treat nausea. It caused an epidemic in which thousands of babies were born with deformed or missing limbs. Women employed during the 1920s as painters of luminescent clock dials were unwittingly exposed to radium from the paint as they licked their brushes. Many died, either from anemia or from bone cancer. These cases later alerted doctors to the dangers of radioactivity and subsequent radiation injury. Other types of toxic bone disease include fluoride and lead poisoning and overexposure to X rays. Tumors. Bone tumors, although not common, are not rare; benign tumors are more common than malignant ones (sarcomas). Metastatic tumors--those which arise primarily in another tissue and spread by the blood to the skeleton, where they usually grow in many places at once--are very common in bones, although tumors originating in bones are not. The skeleton is second only to the lung more follows -- press <RETURN> (P for previous page) as a site for metastases of CANCER. More fatalities and greater pain are associated with metastases of bone than with any other type of cancer. Treatments. Treatments for bone diseases vary as widely as the causes. Physical disorders often require mechanical therapy--for instance, plaster casts for fractures and braces and splints for support. Drugs are used for metabolic problems, and antibiotics for infections. Corrective surgery benefits many people having such diseases as scoliosis. Therapy can involve REHABILITATION MEDICINE, by which victims of injury, deformity, and amputation can learn how to function as normally as possible. JONATHAN COHEN, M.D. Bibliography: Aegerter, Ernest, and Kirkpatrick, John A., Jr., Orthopedic Diseases (1975); Jaffe, Henry L., Metabolic, Degenerative, and Inflammatory Diseases of Bones (1972); Lichtenstein, Louis, Diseases of Bones and Joints, 2d ed. (1975); Maroteaux, Pierre, Bone Diseases of Children, trans. by Herbert J. Kaufmann (1979). ------------------------------------------------------------------------------- <RETURN> to continue, <Q>UIT for a new search, or <R> to REPEAT this display 1 - Bone diseases 2 - Geriatrics 3 - Osteoporosis ALL ITEMS HAVE BEEN DISPLAYED. ENTER <LINE NUMBER> TO DISPLAY FULL RECORD <Q>UIT FOR NEW SEARCH Q You began with a W search on: OSTEOPOROSIS Type S to try your search in another database, or R to repeat your search in Encyclopedia or <RETURN> for a new search:S Your initial search was: OSTEOPOROSIS Select the catalog you wish to try next: The following databases are currently available: 1. ASU General Catalog 2. Encyclopedia 3. Library News and Help Enter the NUMBER of your choice, and press the <RETURN> key >>1 WORKING... this takes a sec... SELECTED DATABASE: ASU General Catalog OSTEOPOROSIS 00011 ITEMS You may make your search more specific (and reduce the size of the list) by adding another word to your search. The result will be items in your current list that also contain the new word. to ADD a new word, enter it, <D>ISPLAY to see the current list, or <Q>UIT for a new search: NEW WORD(S): OSTEOPOROSIS WORKING... OSTEOPOROSIS + OSTEOPOROSIS 00011 ITEMS You now have: OSTEOPOROSIS + OSTEOPOROSIS 00011 ITEMS You may make your search more specific (and reduce the size of the list) by adding another word to your search. The result will be items in your current list that also contain the new word. to ADD a new word, enter it, <D>ISPLAY to see the current list, or <Q>UIT for a new search: NEW WORD(S): SYMPTOMS WORKING... SYMPTOMS is in the data base, but did not occur with OSTEOPOROSIS + OSTEOPOROSIS You now have: OSTEOPOROSIS + OSTEOPOROSIS 00011 ITEMS You may make your search more specific (and reduce the size of the list) by adding another word to your search. The result will be items in your current list that also contain the new word. to ADD a new word, enter it, <D>ISPLAY to see the current list, or <Q>UIT for a new search: NEW WORD(S): TESTS WORKING... TESTS is in the data base, but did not occur with OSTEOPOROSIS + OSTEOPOROSIS You now have: OSTEOPOROSIS + OSTEOPOROSIS 00011 ITEMS You may make your search more specific (and reduce the size of the list) by adding another word to your search. The result will be items in your current list that also contain the new word. to ADD a new word, enter it, <D>ISPLAY to see the current list, or <Q>UIT for a new search: NEW WORD(S): DETECTION WORKING... OSTEOPOROSIS + OSTEOPOROSIS + DETECTION 00002 ITEMS You now have: OSTEOPOROSIS + OSTEOPOROSIS + DETECTION 00002 ITEMS PREPARING YOUR DISPLAY -- HOLD ON... 1 ASU see record 1987 The Osteoporotic syndrome : detection, preventi RC931 .O73 O79 1987 2 ASU SCI STKS 1983 The Osteoporotic syndrome : detection, preventi RC931 .O73 O79 1983 ALL ITEMS HAVE BEEN DISPLAYED. ENTER <LINE NUMBER> TO DISPLAY FULL RECORD <Q>UIT FOR NEW SEARCH 1 WORKING... ------------------------------------------------------------------------------- TITLE(s): The Osteoporotic syndrome : detection, prevention, and treatment / edited by Louis V. Avioli. 2nd ed. Orlando : Grune & Stratton, c1987. viii, 183 p. : ill. ; 23 cm. Includes bibliographies and index. OTHER ENTRIES: Osteoporosis. Osteoporosis Age factors. Women Diseases. Avioli, Louis V. CALL #: RC931 .O73 O79 1987 LOCN: SCI STKS STATUS: Not checked out -- CALL #: RC931 .O73 O79 1987 LOCN: WEST STKS STATUS: Not checked out -- ------------------------------------------------------------------------------- <RETURN> to continue, <Q>UIT for a new search, or <R> to REPEAT this display Q You began with a W search on: OSTEOPOROSIS Type S to try your search in another database, or R to repeat your search in ASU General Catalog or <RETURN> for a new search:S Your initial search was: OSTEOPOROSIS Select the catalog you wish to try next: The following databases are currently available: 1. ASU General Catalog 2. Encyclopedia 3. Library News and Help Enter the NUMBER of your choice, and press the <RETURN> key >>3 WORKING... Your first step is to select the NEWS file you wish to consult. News is currently available for: 1. General Catalog news 2. Library Hours 3. General system news 4. Library Conduct TYPE the NUMBER of the news file you wish to read, and press the <RETURN> key. ENTER NUMBER:3 WORKING... ********************* NEWS OF THE PUBLIC ACCESS CATALOG ********************** A project of CARL and Arizona State University 23 JULY 1987 Welcome to the ASU Public Access Catalog ! Current database size: ASU System -- Approx. 875,000 records This database contains bibliographic records converted from the ALIS format to CARL format. Just under 900,000 records are included; all are fully indexed. PRESS <RETURN> TO CONTINUE ASU SYSTEM HARDWARE The computer hardware used with this system is a four (4) processor Tandem NonStopII System. The computer handles over a million fast accurate transactions every day. The reliablity of the Tandem system significantly reduces the risk of system failure and protects the ASU data base from damage caused by electronic malfunctions. A Tandem system consists of 2 to 16 processors, each working independently but concurrently. A Tandem user can start with a minimum size system and expand incrementally as needs grow. Major financial institutions and corporations worldwide in over 25 industries rely on Tandem for unerring, assured system performance. The current CARL hardware configuration looks like this: TANDEM NONSTOP II SYSTEM PRESS <RETURN> TO CONTINUE 4 PROCESSORS TOTAL 18 MILLION BYTES OF MAIN MEMORY 16 264 MILLION BYTE (FORMATTED) "WINCHESTER" DISC DRIVES 4 240 MILLION BYTE (FORMATTED) REMOVABLE PACK DISC DRIVES 2 125 I.P.S. TAPE DRIVE 128 CONFIGURED ASYNC TERMINAL PORTS APPROXIMATELY 100 ACTIVE AT THIS TIME END OF NEWS..... PRESS <RETURN> TO CONTINUE The following databases are currently available: 1. ASU General Catalog 2. Encyclopedia 3. Library News and Help Enter the NUMBER of your choice, and press the <RETURN> key >>Q WORKING... this takes a sec... WELCOME TO ASU LIBRARIES ONLINE CATALOG (version 74) Developed by The Colorado Alliance of Research Libraries (CARL) and Arizona State University PRESS <RETURN> TO START PROGRAM: M WORKING... The following databases are currently available: 1. ASU General Catalog 2. Encyclopedia 3. Library News and Help Enter the NUMBER of your choice, and press the <RETURN> key >> WORKING... I NEED THE NUMBER FOR YOUR SELECTION -- PLEASE TRY AGAIN... The following databases are currently available: 1. ASU General Catalog 2. Encyclopedia 3. Library News and Help Enter the NUMBER of your choice, and press the <RETURN> key >>Q WORKING... WELCOME TO ASU LIBRARIES ONLINE CATALOG (version 74) Developed by The Colorado Alliance of Research Libraries (CARL) and Arizona State University PRESS <RETURN> TO START PROGRAM: Q M t NO CARRIER